KIVO Med
The first week of embryonic development
Relate sperm transit, fertilization, cleavage and tubal migration from gametes to blastocyst during the first seven days.
- 99 explained questions
- 30 flashcards
- 172 estimated course minutes
Updated
What you will learn
- Describe sperm transit and capacitation in the female genital tract.
- Explain the molecular stages of fertilization and their cellular and nuclear consequences.
- Follow cleavage from the fertilized egg to morula and blastocyst.
- Relate cleavage chronology to migration of the conceptus through the uterine tube.
Course outline
Map of the first week
Build the trajectory from gametes to blastocyst between fertilization and the beginning of implantation.
10 min
Transit and capacitation of spermatozoa
Follow the barriers and transformations that carry sperm from the vagina to the tube and make them capable of fertilization.
22 min
Gamete encounter and passage through the corona radiata
Locate fertilization and explain how the oocyte and sperm meet and cross the corona radiata.
18 min
Acrosome reaction and penetration of the zona pellucida
Describe membrane fusion and the action of acrosomal enzymes that allow sperm to cross the zona pellucida.
14 min
Consequences of sperm penetration
Relate the block to polyspermy, completion of meiosis II and zygote formation to the start of the first cleavage.
22 min
Results and anomalies of fertilization
Identify the new genome, the diploid chromosome number and anomalies of chromosome number or distribution.
20 min
Cleavage and morula formation
Describe the cleavage pattern and follow blastomere chronology to the morula free in the uterine cavity.
20 min
Transformation of the morula into a blastocyst
Relate compaction and polarization to separation of trophoblast, embryonic knob and blastocoele.
20 min
Tubal migration
Explain how the egg, morula and then blastocyst travel from the ampulla to the uterine cavity through the tube.
14 min
Clinical landmarks: ovulation and FIVETE
Relate the thermal curve of ovulation to the stages of in-vitro fertilization with embryo transfer.
12 min
Study and practise with KIVO Med
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In the same subject
Foundations of embryology
Place human development in time while mastering embryological vocabulary and the principles of meiosis.
Mitosis and meiosis
Two cell-division programmes: preservation of the diploid genome by mitosis, then reduction, recombination, and gamete production by meiosis.
Oogenesis and folliculogenesis
Follow the origin, chronology, meiotic divisions, follicular maturation, and regulation of the female germ line.
Spermatogenesis: the male germ line
Describe sperm production, maturation, kinetics and endocrine regulation.