KIVO Med
Ligand–receptor interactions and signal transduction
From chemical messages to their receptors, transduction pathways, regulation and cellular effects.
- 15 explained questions
- 15 flashcards
- 78 estimated course minutes
Updated
What you will learn
- Distinguish chemical communication routes and the main classes of ligands.
- Relate receptor location to whether a ligand is lipid-soluble or water-soluble.
- Describe the major signal-transduction pathways and their amplification mechanisms.
- Explain receptor-number regulation and the cellular consequences of ligand–receptor interaction.
Course outline
From chemical message to cellular response
A whole-course map of the chemical communications that regulate organs and homeostasis.
8 min
Ligands and receptors: nature, location and properties
A ligand’s solubility determines its access to the cell and the location of its receptor.
13 min
Receptor activation and transduction pathways
A first messenger changes its receptor; the events between this activation and the response constitute transduction.
20 min
Second messengers, amplification and gene transcription
cAMP, IP3–DAG and calcium pathways convert a membrane signal into an intracellular cascade.
22 min
Ligand–receptor regulation and cellular consequences
Receptor number and affinity vary with physiological conditions and adjust target-cell responsiveness.
15 min
Study and practise with KIVO Med
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Educational resources for medical studies; they do not replace your faculty’s teaching or medical advice.
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