KIVO Med
Complex lipids: structure and properties
Glycerophospholipids, sphingolipids, amphiphilicity, hydrolysis and membrane, signalling and recognition roles.
- 30 explained questions
- 27 flashcards
- 216 estimated course minutes
Updated
What you will learn
- Recognize the architecture and classes of glycerophospholipids and sphingolipids.
- Relate amphiphilicity, hydrolysis and bilayer organization to biological properties.
- Describe sphingomyelins, cerebrosides, gangliosides and their cellular roles.
Course outline
Lipids built for interfaces
Complex lipids combine a hydrophobic anchor with a polar head that builds membranes and carries signals.
12 min
Glycerophospholipids: building the phosphatidic skeleton
Two fatty acids, glycerol-3-phosphate and an alcohol X form the major family of membrane phospholipids.
22 min
Glycerophospholipid classes: the head defines identity
Changing the alcohol linked to phosphate changes the phospholipid’s name, charge, location and sometimes function.
32 min
Glycerophospholipid derivatives
Removing one chain or replacing an ester bond with an ether produces molecules with new properties.
20 min
Amphiphilicity, assemblies and hydrolysis
Heads and tails direct assembly in water, while each hydrolysis cleaves a defined bond.
32 min
Sphingosine and ceramide: building the other skeleton
A C18 amino alcohol replaces glycerol; adding a fatty acid to its amine forms ceramide.
24 min
Sphingomyelins, cerebrosides and sulfatides
Phosphocholine or a sugar attached to ceramide defines sphingolipids that are particularly abundant in membranes and myelin.
24 min
Gangliosides: an exposed carbohydrate identity
A sialic-acid-containing oligosaccharide turns ceramide into an acidic recognition glycolipid.
26 min
Connecting architecture, interface and signal
Amphiphilicity organises membranes, bile, surfactant and lipoproteins; specialised heads add recognition and signalling.
24 min
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