KIVO Med
Peptides: bonds, properties and analysis
Build, represent and analyse a peptide, from its amide bond to its biological roles.
- 43 explained questions
- 33 flashcards
- 261 estimated course minutes
Updated
What you will learn
- Describe formation, geometry and polarity of the peptide bond.
- Represent, name and classify a peptide sequence.
- Explain peptide properties, hydrolysis and analytical methods.
- Relate several biological peptides to their described structure and function.
Course outline
From amino acid to peptide message
Locate the peptide chain, its residues, and its orientation before studying its geometry, properties, and analytical methods.
12 min
Forming the bond and orienting the chain
Follow separately the condensation that creates the amide and the preservation of the N- and C-terminal ends.
19 min
A planar, rigid, polar amide bond
Infer local peptide geometry from resonance, then distinguish the amide plane, cis–trans, rotation angles, and polarity.
36 min
Writing, naming, and cyclising a sequence
Read a chain from N to C, distinguish backbone from side chains, apply nomenclature, and recognise head-to-tail cyclisation.
20 min
Classifying by size, form, function, and origin
Apply four classification axes separately and interpret their conventional thresholds cautiously.
20 min
Solubility, charge, and UV absorption
Relate size, composition, ionisable groups, and aromatic residues separately to measurable peptide properties.
21 min
Chemical reactivity and disulphide bridges
Study esterification, cysteine redox chemistry, colour tests, and hydrolysis as separate reactions.
26 min
Synthesis, maturation, and enzymatic hydrolysis
Distinguish ribosomal construction, maturation, non-ribosomal synthesis, and terminal or internal cleavage.
25 min
Hydrolysing and quantifying amino acids
Choose a hydrolysis, separate released AAs, then reveal and quantify each constituent.
24 min
Reconstructing the sequence
Cross terminal information with specifically cleaved fragments to place residues in order.
32 min
From peptides to biological functions
Compare peptides by sequence, disulphide bridges, location, and biological function.
26 min
Study and practise with KIVO Med
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Educational resources for medical studies; they do not replace your faculty’s teaching or medical advice.
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