KIVO Med
Lipid digestion and absorption
Emulsification, gastric and intestinal hydrolysis, mixed micelles and absorption into portal blood or chylomicrons.
- 20 explained questions
- 18 flashcards
- 104 estimated course minutes
Updated
What you will learn
- Explain why emulsification is required for water-soluble enzymes to act.
- Distinguish gastric and intestinal digestion and match enzymes to substrates.
- Describe mixed-micelle formation and transport to the brush border.
- Predict the portal, enterocyte, lymphatic and chylomicron fate of absorbed products.
Course outline
Moving lipids through an aqueous environment
Lipid digestion transforms a hydrophobic mass into products that can be transported to the enterocyte.
10 min
Emulsification: making an enzymatic interface
Dispersing fats multiplies boundaries where an aqueous enzyme can meet a lipid substrate.
14 min
In the stomach: mixing and partial hydrolysis
The gastric phase disperses fats and begins hydrolysis mainly of short- and medium-chain triglycerides.
14 min
In the intestine: bile and pancreatic enzymes
Bile salts stabilise interfaces; each pancreatic enzyme then hydrolyses a defined lipid class.
26 min
Mixed micelles: keeping and delivering products
Bile salts build a hydrophilic surface around lipid contents destined for the brush border.
16 min
Absorption: choosing between portal blood and lymph
The enterocyte sends small molecules to blood and reassembles other lipids before chylomicron export.
24 min
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